{"id":3043,"date":"2025-11-21T18:27:25","date_gmt":"2025-11-21T18:27:25","guid":{"rendered":"https:\/\/theinformantusa.com\/?p=3043"},"modified":"2025-11-21T18:27:26","modified_gmt":"2025-11-21T18:27:26","slug":"stanford-scientists-cure-type-1-diabetes-in-mice-with-immune-reboot-transplant","status":"publish","type":"post","link":"https:\/\/theinformantusa.com\/?p=3043","title":{"rendered":"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT"},"content":{"rendered":"\n<h2 class=\"wp-block-heading has-medium-font-size\"><em>A breakthrough dual-transplant technique stops the autoimmune attack without insulin or immunosuppressants \u2014 offering hope for future human treatments.<\/em><\/h2>\n\n\n\n<p>Researchers at <strong>Stanford University<\/strong>, led by <strong>Dr. Seung K. Kim<\/strong>, have successfully <strong>cured type 1 diabetes in mice<\/strong> using a groundbreaking treatment that combines <strong>blood stem cell transplants<\/strong> with <strong>donor pancreatic islets<\/strong> \u2014 even when donor and recipient were <strong>immunologically incompatible<\/strong>.<\/p>\n\n\n\n<p>The study, published in the <em>Journal of Clinical Investigation<\/em>, describes a procedure that <strong>\u201creboots\u201d the immune system<\/strong>, stopping it from attacking insulin-producing beta cells. Remarkably, the treated mice required <strong>no chronic immunosuppressive drugs<\/strong> and <strong>no external insulin<\/strong> during <strong>six months<\/strong> of follow-up.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\">HOW THE TREATMENT WORKS<\/h2>\n\n\n\n<p>The therapy involves:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li><strong>Transplanting donor blood stem cells<\/strong>, which reset the immune system.<\/li>\n\n\n\n<li><strong>Transplanting pancreatic islet cells<\/strong>, which restore natural insulin production.<\/li>\n<\/ol>\n\n\n\n<p>This dual approach prevents both <strong>graft rejection<\/strong> and <strong>autoimmune destruction<\/strong> of beta cells \u2014 the two major obstacles to curing type 1 diabetes.<\/p>\n\n\n\n<p>The results were extraordinary:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>19 out of 19 healthy mice<\/strong> had complete protection of donor islets.<\/li>\n\n\n\n<li><strong>9 out of 9 diabetic mice<\/strong> were fully cured, maintaining normal glucose levels.<\/li>\n<\/ul>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading has-medium-font-size\"> IMPLICATIONS FOR HUMANS<\/h2>\n\n\n\n<p>The breakthrough offers real hope for a future cure that:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong>Eliminates lifelong insulin injections<\/strong><\/li>\n\n\n\n<li><strong>Removes the need for toxic immunosuppressants<\/strong><\/li>\n\n\n\n<li><strong>Restores natural insulin regulation<\/strong><\/li>\n<\/ul>\n\n\n\n<p>Researchers believe the technique could also be adapted to treat other <strong>autoimmune diseases<\/strong>, including <strong>rheumatoid arthritis<\/strong> and <strong>lupus<\/strong>.<\/p>\n\n\n\n<p>However, challenges remain \u2014 particularly the <strong>limited supply of donor islets<\/strong> from deceased donors. Future studies may explore lab-grown or stem-cell-derived alternatives.<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A breakthrough dual-transplant technique stops the autoimmune attack without insulin or immunosuppressants \u2014 offering hope for future human treatments. Researchers at Stanford University, led by Dr. Seung K. Kim, have successfully cured type 1 diabetes in mice using a groundbreaking treatment that combines blood stem cell transplants with donor pancreatic islets \u2014 even when donor [&hellip;]<\/p>\n","protected":false},"author":2,"featured_media":3044,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[27],"tags":[1042,1041,1037,1040,1039,1038],"class_list":["post-3043","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-lifestyle","tag-autoimmune-disease-cure","tag-immune-reboot-transplant","tag-islet-transplant-breakthrough","tag-journal-of-clinical-investigation-diabetes-study","tag-stanford-research-diabetes","tag-type-1-diabetes-cure"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.0 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT - The Informant USA<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/theinformantusa.com\/?p=3043\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT - The Informant USA\" \/>\n<meta property=\"og:description\" content=\"A breakthrough dual-transplant technique stops the autoimmune attack without insulin or immunosuppressants \u2014 offering hope for future human treatments. Researchers at Stanford University, led by Dr. Seung K. Kim, have successfully cured type 1 diabetes in mice using a groundbreaking treatment that combines blood stem cell transplants with donor pancreatic islets \u2014 even when donor [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/theinformantusa.com\/?p=3043\" \/>\n<meta property=\"og:site_name\" content=\"The Informant USA\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/profile.php?id=61575215453941\" \/>\n<meta property=\"article:published_time\" content=\"2025-11-21T18:27:25+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-11-21T18:27:26+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26-1024x576.png\" \/>\n\t<meta property=\"og:image:width\" content=\"1024\" \/>\n\t<meta property=\"og:image:height\" content=\"576\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"THE INFORMANT USA EDITORIAL\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@TheInformantUSA\" \/>\n<meta name=\"twitter:site\" content=\"@TheInformantUSA\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"THE INFORMANT USA EDITORIAL\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/theinformantusa.com\/?p=3043#article\",\"isPartOf\":{\"@id\":\"https:\/\/theinformantusa.com\/?p=3043\"},\"author\":{\"name\":\"THE INFORMANT USA EDITORIAL\",\"@id\":\"https:\/\/theinformantusa.com\/#\/schema\/person\/a225d759aad5f3e3286992983049831b\"},\"headline\":\"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT\",\"datePublished\":\"2025-11-21T18:27:25+00:00\",\"dateModified\":\"2025-11-21T18:27:26+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/theinformantusa.com\/?p=3043\"},\"wordCount\":248,\"commentCount\":0,\"publisher\":{\"@id\":\"https:\/\/theinformantusa.com\/#organization\"},\"image\":{\"@id\":\"https:\/\/theinformantusa.com\/?p=3043#primaryimage\"},\"thumbnailUrl\":\"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26.png\",\"keywords\":[\"autoimmune disease cure\",\"immune reboot transplant\",\"islet transplant breakthrough\",\"Journal of Clinical Investigation diabetes study\",\"Stanford research diabetes\",\"type 1 diabetes cure\"],\"articleSection\":[\"LIFESTYLE\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\/\/theinformantusa.com\/?p=3043#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/theinformantusa.com\/?p=3043\",\"url\":\"https:\/\/theinformantusa.com\/?p=3043\",\"name\":\"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT - The Informant USA\",\"isPartOf\":{\"@id\":\"https:\/\/theinformantusa.com\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/theinformantusa.com\/?p=3043#primaryimage\"},\"image\":{\"@id\":\"https:\/\/theinformantusa.com\/?p=3043#primaryimage\"},\"thumbnailUrl\":\"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26.png\",\"datePublished\":\"2025-11-21T18:27:25+00:00\",\"dateModified\":\"2025-11-21T18:27:26+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/theinformantusa.com\/?p=3043#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/theinformantusa.com\/?p=3043\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/theinformantusa.com\/?p=3043#primaryimage\",\"url\":\"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26.png\",\"contentUrl\":\"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26.png\",\"width\":1920,\"height\":1080},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/theinformantusa.com\/?p=3043#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Portada\",\"item\":\"https:\/\/theinformantusa.com\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/theinformantusa.com\/#website\",\"url\":\"https:\/\/theinformantusa.com\/\",\"name\":\"The Informant USA\",\"description\":\"\",\"publisher\":{\"@id\":\"https:\/\/theinformantusa.com\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/theinformantusa.com\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/theinformantusa.com\/#organization\",\"name\":\"The Informant USA\",\"url\":\"https:\/\/theinformantusa.com\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/theinformantusa.com\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/05\/THE-INFORMANT-USA-OFI-B.png\",\"contentUrl\":\"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/05\/THE-INFORMANT-USA-OFI-B.png\",\"width\":1080,\"height\":1080,\"caption\":\"The Informant USA\"},\"image\":{\"@id\":\"https:\/\/theinformantusa.com\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/profile.php?id=61575215453941\",\"https:\/\/x.com\/TheInformantUSA\",\"https:\/\/www.instagram.com\/theinformantusa\/\",\"https:\/\/www.tiktok.com\/@theinformantusa\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/theinformantusa.com\/#\/schema\/person\/a225d759aad5f3e3286992983049831b\",\"name\":\"THE INFORMANT USA EDITORIAL\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/theinformantusa.com\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/56273392fc0176bb507cd935f1cfc790a1db84203e9b0e0691468fcdd7dc8530?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/56273392fc0176bb507cd935f1cfc790a1db84203e9b0e0691468fcdd7dc8530?s=96&d=mm&r=g\",\"caption\":\"THE INFORMANT USA EDITORIAL\"},\"url\":\"https:\/\/theinformantusa.com\/?author=2\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT - The Informant USA","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/theinformantusa.com\/?p=3043","og_locale":"en_US","og_type":"article","og_title":"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT - The Informant USA","og_description":"A breakthrough dual-transplant technique stops the autoimmune attack without insulin or immunosuppressants \u2014 offering hope for future human treatments. Researchers at Stanford University, led by Dr. Seung K. Kim, have successfully cured type 1 diabetes in mice using a groundbreaking treatment that combines blood stem cell transplants with donor pancreatic islets \u2014 even when donor [&hellip;]","og_url":"https:\/\/theinformantusa.com\/?p=3043","og_site_name":"The Informant USA","article_publisher":"https:\/\/www.facebook.com\/profile.php?id=61575215453941","article_published_time":"2025-11-21T18:27:25+00:00","article_modified_time":"2025-11-21T18:27:26+00:00","og_image":[{"width":1024,"height":576,"url":"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26-1024x576.png","type":"image\/png"}],"author":"THE INFORMANT USA EDITORIAL","twitter_card":"summary_large_image","twitter_creator":"@TheInformantUSA","twitter_site":"@TheInformantUSA","twitter_misc":{"Written by":"THE INFORMANT USA EDITORIAL","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/theinformantusa.com\/?p=3043#article","isPartOf":{"@id":"https:\/\/theinformantusa.com\/?p=3043"},"author":{"name":"THE INFORMANT USA EDITORIAL","@id":"https:\/\/theinformantusa.com\/#\/schema\/person\/a225d759aad5f3e3286992983049831b"},"headline":"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT","datePublished":"2025-11-21T18:27:25+00:00","dateModified":"2025-11-21T18:27:26+00:00","mainEntityOfPage":{"@id":"https:\/\/theinformantusa.com\/?p=3043"},"wordCount":248,"commentCount":0,"publisher":{"@id":"https:\/\/theinformantusa.com\/#organization"},"image":{"@id":"https:\/\/theinformantusa.com\/?p=3043#primaryimage"},"thumbnailUrl":"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26.png","keywords":["autoimmune disease cure","immune reboot transplant","islet transplant breakthrough","Journal of Clinical Investigation diabetes study","Stanford research diabetes","type 1 diabetes cure"],"articleSection":["LIFESTYLE"],"inLanguage":"en-US","potentialAction":[{"@type":"CommentAction","name":"Comment","target":["https:\/\/theinformantusa.com\/?p=3043#respond"]}]},{"@type":"WebPage","@id":"https:\/\/theinformantusa.com\/?p=3043","url":"https:\/\/theinformantusa.com\/?p=3043","name":"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT - The Informant USA","isPartOf":{"@id":"https:\/\/theinformantusa.com\/#website"},"primaryImageOfPage":{"@id":"https:\/\/theinformantusa.com\/?p=3043#primaryimage"},"image":{"@id":"https:\/\/theinformantusa.com\/?p=3043#primaryimage"},"thumbnailUrl":"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26.png","datePublished":"2025-11-21T18:27:25+00:00","dateModified":"2025-11-21T18:27:26+00:00","breadcrumb":{"@id":"https:\/\/theinformantusa.com\/?p=3043#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/theinformantusa.com\/?p=3043"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/theinformantusa.com\/?p=3043#primaryimage","url":"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26.png","contentUrl":"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/11\/the-informant-26.png","width":1920,"height":1080},{"@type":"BreadcrumbList","@id":"https:\/\/theinformantusa.com\/?p=3043#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Portada","item":"https:\/\/theinformantusa.com\/"},{"@type":"ListItem","position":2,"name":"STANFORD SCIENTISTS CURE TYPE 1 DIABETES IN MICE WITH IMMUNE \u201cREBOOT\u201d TRANSPLANT"}]},{"@type":"WebSite","@id":"https:\/\/theinformantusa.com\/#website","url":"https:\/\/theinformantusa.com\/","name":"The Informant USA","description":"","publisher":{"@id":"https:\/\/theinformantusa.com\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/theinformantusa.com\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/theinformantusa.com\/#organization","name":"The Informant USA","url":"https:\/\/theinformantusa.com\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/theinformantusa.com\/#\/schema\/logo\/image\/","url":"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/05\/THE-INFORMANT-USA-OFI-B.png","contentUrl":"https:\/\/theinformantusa.com\/wp-content\/uploads\/2025\/05\/THE-INFORMANT-USA-OFI-B.png","width":1080,"height":1080,"caption":"The Informant USA"},"image":{"@id":"https:\/\/theinformantusa.com\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/profile.php?id=61575215453941","https:\/\/x.com\/TheInformantUSA","https:\/\/www.instagram.com\/theinformantusa\/","https:\/\/www.tiktok.com\/@theinformantusa"]},{"@type":"Person","@id":"https:\/\/theinformantusa.com\/#\/schema\/person\/a225d759aad5f3e3286992983049831b","name":"THE INFORMANT USA EDITORIAL","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/theinformantusa.com\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/56273392fc0176bb507cd935f1cfc790a1db84203e9b0e0691468fcdd7dc8530?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/56273392fc0176bb507cd935f1cfc790a1db84203e9b0e0691468fcdd7dc8530?s=96&d=mm&r=g","caption":"THE INFORMANT USA EDITORIAL"},"url":"https:\/\/theinformantusa.com\/?author=2"}]}},"_links":{"self":[{"href":"https:\/\/theinformantusa.com\/index.php?rest_route=\/wp\/v2\/posts\/3043","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/theinformantusa.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/theinformantusa.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/theinformantusa.com\/index.php?rest_route=\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/theinformantusa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3043"}],"version-history":[{"count":1,"href":"https:\/\/theinformantusa.com\/index.php?rest_route=\/wp\/v2\/posts\/3043\/revisions"}],"predecessor-version":[{"id":3045,"href":"https:\/\/theinformantusa.com\/index.php?rest_route=\/wp\/v2\/posts\/3043\/revisions\/3045"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/theinformantusa.com\/index.php?rest_route=\/wp\/v2\/media\/3044"}],"wp:attachment":[{"href":"https:\/\/theinformantusa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3043"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/theinformantusa.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=3043"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/theinformantusa.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=3043"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}